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The StcE Protease Contributes to Intimate Adherence of Enterohemorrhagic<i>Escherichia coli</i>O157:H7 to Host Cells

24 Feb 2005

Abstract excerpt

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a diarrheal pathogen that causes attaching and effacing (A/E) lesions on intestinal epithelial cells. Strains of the O157 serogroup carry the large virulence plasmid pO157, which encodes the etp type II secretion system that secretes the genetically linked zinc metalloprotease StcE. The Ler regulator controls expression of many genes involved in A/E lesion...

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PMID: 15731026
DOI: 10.1128/iai.73.3.1295-1303.2005

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