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Circulating transcriptome reveals markers of atherosclerosis

22 Feb 2005

Abstract excerpt

Circulating monocytes mediate inflammation in atherosclerosis and may serve as easily accessible reporters of disease. To search for markers of atherosclerosis, we compared the in vivo transcriptomes of monocytes purified from patients undergoing carotid endarterectomy and normal subjects by using the serial analysis of gene expression technique. We selected a subset of differentially expressed monocyte-specific...

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PMID: 15728378
DOI: 10.1073/pnas.0408032102

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