Article
1H-MRS alterations in the cerebellum of patients with familial hemiplegic migraine type 1.
Neurology - 22 Feb 2005
Dichgans M, Herzog J, Freilinger T, Wilke M, Auer D P
Abstract excerpt
BACKGROUND: About 20% of patients with familial hemiplegic migraine (FHM) develop progressive cerebellar signs. Genetic studies have established an association with mutations in the CACNA1A gene. However, the mechanisms underlying cerebellar involvement are largely unknown. OBJECTIVE: To use proton MR spectroscopy (1H-MRS) to investigate metabolic alterations in the cerebellum as well as cortical regions known to...
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