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Article

ABL-MYC retroviral infection elicits bone marrow plasma cell tumors in Bcl-X(L) transgenic mice.

Leukemia research - 1 Apr 2005

Linden Michael, Kirchhof Nicole, Kvitrud Mary, Van Ness Brian

Abstract excerpt

Multiple myeloma is characterized by the accumulation of malignant plasma cells in the bone marrow. While there have been many attempts to genetically recapitulate this disease in animal models, few reports describe plasma cell tumors that exhibit bone marrow involvement. We recently described a Bcl-X(L) transgenic mouse that developed polyclonal non-malignant B-cell expansions in the bone marrow and lymphoid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15725478
DOI: 10.1016/j.leukres.2004.09.007

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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