Article
Glutathione-S-transferase and p53 polymorphisms in cervical carcinogenesis.
Gynecologic oncology - 1 Mar 2005
Ueda Masatsugu, Hung Yao-Ching, Terai Yoshito, Saito Junko, Nunobiki Osamu, Noda Sadamu, Ueki Minoru
Abstract excerpt
OBJECTIVE: To investigate the clinical significance of glutathione-S-transferase GSTM1, GSTT1 and p53 codon 72 polymorphisms in cervical carcinogenesis. METHODS: GSTM1, GSTT1 and p53 codon 72 polymorphisms together with human papillomavirus (HPV) types were examined in a total of 198 cervical smear samples using multiplex polymerase chain reaction (PCR) and PCR restriction fragment length polymorphism (RFLP)...
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