Article
Null genotypes of GSTM1 and GSTT1 contribute to risk of cervical neoplasia: an evidence-based meta-analysis.
PloS one - 1 Jan 2011
Gao Lin-Bo, Pan Xin-Min, Li Li-Juan, Liang Wei-Bo, Bai Peng, Rao Li, Su Xiao-Wei, Wang Tao, Zhou Bin, Wei Yong-Gang, Zhang Lin
Abstract excerpt
BACKGROUND AND OBJECTIVES: Glutathione S-transferases (GSTs) are multifunctional enzymes that play a key role in the detoxification of varieties of both endogenous products of oxidative stress and exogenous carcinogens. METHODS: In this meta-analysis, twenty-five studies were identified by searching PubMed, EMBASE, ISI Web of Science and CBM databases: 23 evaluated GSTM1 and 19 evaluated GSTT1. Crude odds ratios...
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