Article
Opposing effects of emphysema, hay fever, and select genetic variants on lung cancer risk.
American journal of epidemiology - 1 Mar 2005
Schabath Matthew B, Delclos George L, Martynowicz Marek M, Greisinger Anthony J, Lu Charles, Wu Xifeng, Spitz Margaret R
Abstract excerpt
The authors compared histories of nonmalignant respiratory diseases (asthma, bronchitis, emphysema, hay fever, and pneumonia) in 1,553 lung cancer patients and 1,375 healthy controls enrolled in a Texas case-control study from 1995 to 2003. They incorporated data on two biologically relevant polymorphic genes, matrix metalloproteinase-1 and myeloperoxidase. Emphysema was associated with a statistically...
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