Article
Editing at the crossroad of innate and adaptive immunity.
Science (New York, N.Y.) - 18 Feb 2005
Turelli Priscilla, Trono Didier
Abstract excerpt
Genetic information can be altered through the enzymatic modification of nucleotide sequences. This process, known as editing, was originally identified in the mitochondrial RNA of trypanosomes and later found to condition events as diverse as neurotransmission and lipid metabolism in mammals. Recent evidence reveals that editing enzymes may fulfill one of their most essential roles in the defense against...
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