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Article

Review of hemophagocytic lymphohistiocytosis (HLH) in children with focus on Japanese experiences.

Critical reviews in oncology/hematology - 1 Mar 2005

Ishii Eiichi, Ohga Shouichi, Imashuku Shinsaku, Kimura Nobuhiro, Ueda Ikuyo, Morimoto Akira, Yamamoto Ken, Yasukawa Masaki

Abstract excerpt

Hemophagocytic lymphohistiocytosis (HLH) is characterized by fever and hepatosplenomegaly associated with pancytopenia, hypertriglyceridemia and hypofibrinogenemia. Increased levels of cytokines and impaired natural killer activity are biological markers of HLH. HLH can be classified into two dis...

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Source

Identifiers

PMID: 15718147
DOI: 10.1016/j.critrevonc.2004.11.002

Genes

PRF1
FHL2
FHL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15718147-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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