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Article

Conserved non-genic sequences - an unexpected feature of mammalian genomes.

Nature reviews. Genetics - 1 Feb 2005

Dermitzakis Emmanouil T, Reymond Alexandre, Antonarakis Stylianos E

Abstract excerpt

Mammalian genomes contain highly conserved sequences that are not functionally transcribed. These sequences are single copy and comprise approximately 1-2% of the human genome. Evolutionary analysis strongly supports their functional conservation, although their potentially diverse, functional attributes remain unknown. It is likely that genomic variation in conserved non-genic sequences is associated with...

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PMID: 15716910
DOI: 10.1038/nrg1527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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