Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 894T allele of endothelial nitric oxide synthase gene is related to left ventricular mass in African Americans with high-normal blood pressure.

Journal of the National Medical Association - 1 Feb 2005

Lapu-Bula Rigobert, Quarshie Alexander, Lyn Deborah, Oduwole Adefisayo, Pack Cheryl, Morgan Jan, Nkemdiche Sunday, Igho-Pemu Priscilla, Onwuanyi Anekwe, Li Rongling, Ofili Elizabeth

Abstract excerpt

BACKGROUND AND OBJECTIVES: The 894T allele in exon 7 of the endothelial nitric oxide synthase (eNOS) gene has been inconsistently associated with hypertension in different racial groups. Because high-normal blood pressure (BP) confers an increased risk for the development of hypertension and other cardiovascular disorders, including left ventricular hypertrophy (LVH), we tested the hypothesis that the allelic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Circulation

Share to Endothelium, Vascular

Share to Hypertension

Share to Hypertrophy, Left Ventricular

Share to Nitric Oxide Synthase

Share to Nitric Oxide Synthase Type III

Source

Open in PubMed Open full text

Identifiers

PMID: 15712782
PMCID: PMC2568802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 894T allele of endothelial nitric oxide synthase gene is related to left ventricular mass in African Americans with high-normal blood pressure.PMID 15712782Read ↗

A common variant of the eNOS gene (E298D) is an independent risk factor for left ventricular hypertrophy in human essential hypertension.Semantic proximity Read ↗

Natriuretic peptides and the genomics of left-ventricular hypertrophy.Semantic proximity Read ↗

The polymorphism G894 T of endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to essential hypertension (EH) in Morocco.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population-based cohort.Semantic proximity Read ↗

Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China.Semantic proximity Read ↗

Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene polymorphisms (894G > T and -786T > C) and risk of coronary artery disease in a Saudi population.Semantic proximity Read ↗

Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study.Semantic proximity Read ↗

Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African AmericansSemantic proximity Read ↗

Relation of endothelial nitric oxide synthase gene to plasma nitric oxide level, endothelial function, and blood pressure in African Americans.Semantic proximity Read ↗

Ambulatory blood pressure, left ventricular mass and vascular phenotypes in relation to the endothelial nitric oxide synthase gene Glu298Asp and intron 4 polymorphisms in a population-based family study.Semantic proximity Read ↗

[The G894T mutation of the endothelial nitric oxide synthase gene is associated with coronary atherosclerotic heart disease in Chinese].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.