Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product.

doi:10.1128/mcb.12.5.1997-2009.1992

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Article

Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product.

Molecular and cellular biology - 1 May 1992

Longtine M S, Enomoto S, Finstad S L, Berman J

Abstract excerpt

Telomere repeat sequences (TRSs) can dramatically improve the segregation of unstable circular autonomously replicating sequence (ARS) plasmids in Saccharomyces cerevisiae. Deletion analysis demonstrated that yeast TRSs, which conform to the general sequence (C(1-3)A)n, are able to stabilize circular ARS plasmids. A number of TRS clones of different primary sequence and C(1-3)A tract length confer the plasmid...

Topics

Alleles
Base Sequence
Chromosome Deletion
Chromosomes, Fungal
Cloning, Molecular
DNA, Circular
DNA-Binding Proteins
Escherichia coli
Fungal Proteins
Genes, Fungal
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitosis

Mutation

Plasmids

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Saccharomyces cerevisiae

Schizosaccharomyces

Source

Open in PubMed Open full text

Identifiers

PMID: 1569937
DOI: 10.1128/mcb.12.5.1997-2009.1992
PMCID: PMC364370

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1569937-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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