Article
Key role of cysteine residues in catalysis and subcellular localization of sulfur oxygenase-reductase of Acidianus tengchongensis.
Applied and environmental microbiology - 1 Feb 2005
Chen Zhi-Wei, Jiang Cheng-Ying, She Qunxin, Liu Shuang-Jiang, Zhou Pei-Jin
Abstract excerpt
Analysis of known sulfur oxygenase-reductases (SORs) and the SOR-like sequences identified from public databases indicated that they all possess three cysteine residues within two conserved motifs (V-G-P-K-V-C(31) and C(101)-X-X-C(104); numbering according to the Acidianus tengchongensis numbering system). The thio-modifying reagent N-ethylmaleimide and Zn(2+) strongly inhibited the activities of the SORs of A....
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