Article
The blood-brain barrier regulates the expression of a macrophage sialic acid-binding receptor on microglia.
Journal of cell science - 1 Jan 1992
Perry V H, Crocker P R, Gordon S
Abstract excerpt
In vitro the expression of a sialic acid-binding receptor on murine macrophages, sialoadhesin, is regulated by exposure to an inducing agent present in serum. We have used immunocytochemistry to examine the macrophage populations of the nervous system in order to test whether this serum inducing agent (SIA) also regulates sialoadhesin expression in vivo and whether plasma proteins may influence the phenotype of...
Topics
- Animals
- Blood Proteins
- Blood-Brain Barrier
- Brain Chemistry
- Gene Expression Regulation
- Macrophages
- Membrane Glycoproteins
- Mice
- Mice, Inbred BALB C
- Neuroglia
- Phenotype