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Article

Smad pathway‐specific transcriptional regulation of the cell cycle inhibitor p21<sup>WAF1/Cip1</sup>

2 Feb 2005

Abstract excerpt

Transforming growth factor-beta (TGF-beta) inhibits epithelial cell growth, in part via transcriptional induction of the cell cycle inhibitor p21(WAF1/Cip1) (p21). We show that bone morphogenetic protein (BMP)-7 induces higher p21 expression than TGF-beta1 in various epithelial cells. Despite this, BMP-7 only weakly suppresses epithelial cell proliferation, as Id2, a cell cycle-promoting factor, becomes...

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Identifiers

PMID: 15690394
DOI: 10.1002/jcp.20304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Smad pathway‐specific transcriptional regulation of the cell cycle inhibitor p21<sup>WAF1/Cip1</sup>PMID 15690394Read ↗

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