Article
Association of histo-blood group antigens and susceptibility to norovirus infections.
The Journal of infectious diseases - 1 Mar 2005
Rockx Barry H G, Vennema Harry, Hoebe Christian J P A, Duizer Erwin, Koopmans Marion P G
Abstract excerpt
BACKGROUND: Noroviruses (NoVs) are the leading cause of viral gastroenteritis in humans of all ages. Challenge studies that used the NoV prototype strain Norwalk virus (NV) have shown that some individuals are not susceptible to infection, suggesting the absence of a receptor. Recent studies have identified histo-blood group antigens (HBGAs) as possible receptors. Being a nonsecretor and presence of HBGA type B...
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