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Article

Simultaneous over‐expression of the <i>Her2/neu</i> and <i>PTK6</i> tyrosine kinases in archival invasive ductal breast carcinomas

31 Jan 2005

Abstract excerpt

Expression of eight tumour-relevant genes was studied in formalin-fixed, paraffin-embedded tissue from 54 invasive ductal breast carcinomas using quantitative reverse transcription PCR (Q-RT-PCR). Seven of the genes map to chromosome 20q and are potential candidates for gene amplification and over-expression. The Her2/neu oncogene, on chromosome 17q, was investigated in the same tumours. Increased expression was...

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PMID: 15685689
DOI: 10.1002/path.1720

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