Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of change in posture and exercise on repolarization in patients with long QT syndrome with HERG channel mutations.

The Canadian journal of cardiology - 1 Jan 2005

Walker Bruce D, Krahn Andrew D, Klein George J, Skanes Allan C, Yee Raymond, Wang Jian, Hegele Robert A

Abstract excerpt

INTRODUCTION: Congenital long QT syndrome (LQTS) is characterized by syncope and cardiac arrest, often in association with exercise or sudden arousal. It was hypothesized that patients with LQTS with human ether-a-go-go-related gene (HERG) mutations (LQT2) have an abnormal QT adaptation to changes in heart rate induced by exercise and that such abnormalities may be ameliorated by treatment with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenergic beta-Antagonists
Share to Electrocardiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exercise Test

Share to Heart Rate

Share to Long QT Syndrome

Share to Posture

Share to Potassium Channels, Voltage-Gated

Share to Ventricular Remodeling

Source

Identifiers

PMID: 15685300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of change in posture and exercise on repolarization in patients with long QT syndrome with HERG channel mutations.PMID 15685300Read ↗

Genotype- and mutation site-specific QT adaptation during exercise, recovery, and postural changes in children with long-QT syndrome.Semantic proximity Read ↗

Utility of treadmill testing in identification and genotype prediction in long-QT syndrome.Semantic proximity Read ↗

Use of autonomic maneuvers to probe phenotype/genotype discordance in congenital long QT syndrome.Semantic proximity Read ↗

Repolarization dynamics during exercise discriminate between LQT1 and LQT2 genotypes.Semantic proximity Read ↗

Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects.Semantic proximity Read ↗

Gender differences in the long QT syndrome: effects of beta-adrenoceptor blockade.Semantic proximity Read ↗

Abnormal repolarization dynamics revealed in exercise test in long QT syndrome mutation carriers with normal resting QT interval.Semantic proximity Read ↗

Trigger-specific risk factors and response to therapy in long QT syndrome type 2.Semantic proximity Read ↗

Diagnostic value of T-wave morphology changes during "QT stretching" in patients with long QT syndrome.Semantic proximity Read ↗

Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.Semantic proximity Read ↗

Exercise stress test amplifies genotype-phenotype correlation in the LQT1 and LQT2 forms of the long-QT syndrome.Semantic proximity Read ↗

Do LQTS gene single nucleotide polymorphisms alter QTc intervals at rest and during exercise stress testing?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.