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Article

Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG.

Journal of cardiovascular electrophysiology - 1 Jan 2005

Wolpert Christian, Schimpf Rainer, Giustetto Carla, Antzelevitch Charles, Cordeiro Jonathan, Dumaine Robert, Brugada Ramon, Hong Kui, Bauersfeld Urs, Gaita Fiorenzo, Borggrefe Martin

Abstract excerpt

INTRODUCTION: The principal aim of this study was to assess the efficacy of quinidine in suppressing IKr in vitro and in modulating the rate dependence of the QT interval in the "SQT1" form of the short QT syndrome. METHODS AND RESULTS: Graded-intensity bicycle exercise testing was performed off drug in three patients and during oral quinidine in two patients with short QT syndrome and compared to a control group...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ether-A-Go-Go Potassium Channels

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Share to Potassium Channels, Voltage-Gated

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Source

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Identifiers

PMID: 15673388
DOI: 10.1046/j.1540-8167.2005.04470.x
PMCID: PMC1474841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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