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Article

Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

The Journal of biological chemistry - 15 Apr 2005

Lloyd David B, Lira Maruja E, Wood Linda S, Durham L Kathryn, Freeman Thomas B, Preston Gregory M, Qiu Xiayang, Sugarman Eliot, Bonnette Peter, Lanzetti Anthony, Milos Patrice M, Thompson John F

Abstract excerpt

Cholesteryl ester transfer protein (CETP) is an important modulator of high density lipoprotein cholesterol in humans and thus considered to be a therapeutic target for preventing cardiovascular disease. The gene encoding CETP has been shown to be highly variable, with multiple single nucleotide polymorphisms responsible for altering both its transcription and sequence. Examining nine missense variants of CETP,...

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Source

Identifiers

PMID: 15681846
DOI: 10.1074/jbc.M500523200

Genes

CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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