Article
Interleukin-4 gene intron-3 polymorphism is associated with transitional cell carcinoma of the urinary bladder.
BJU international - 1 Feb 2005
Tsai Fuu-Jen, Chang Chao-Hsiang, Chen Chang-Chung, Hsia Te-Chun, Chen Huey-Yi, Chen Wen-Chi
Abstract excerpt
OBJECTIVE: To evaluate whether polymorphism of the interleukin-4 gene exon 3, and of the interleukin-1beta gene exon 5 and promoter region, are associated with transitional cell carcinoma (TCC) of the urinary bladder, as cytokines are hypothesized to be important in cancer formation. PATIENTS, SUBJECTS AND METHODS: The study included 138 patients with TCC of urinary bladder and 105 healthy controls living in the...
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