Article
The gene encoding the I blood group antigen: review of an I for an eye.
Immunohematology - 1 Jan 2004
Reid M E
Abstract excerpt
Unlike most blood group antigen pairs, the I and i antigens are not antithetical (produced by allelic pairs) but, rather, they are reciprocal. The I antigen is formed by the action of an enzyme (a glycosyltransferase), which adds branches onto the i antigen. Thus, branched I antigen is formed at the expense of its precursor, the linear i antigen. The antigens are present on all blood cells and have a wide tissue...
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