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<b>Structure, function and immunogenicity of streptococcal antigen I/II polypeptides</b>

1 Jan 1997

Abstract excerpt

The antigen I/II family of cell-surface-anchored polypeptides in oral streptococci are structurally complex multi-functional adhesins, with multiple ligand-binding sites. Discrete regions within these polypeptides bind human salivary glycoproteins, other microbial cells, and calcium. Sequences within the N-terminal region bind preferentially fluid-phase glycoproteins, while the C-terminal half of the polypeptide...

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PMID: 9044252
DOI: 10.1046/j.1365-2958.1997.2021577.x

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