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Article

A novel I-branching beta-1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression.

Blood - 1 Apr 2003

Inaba Niro, Hiruma Toru, Togayachi Akira, Iwasaki Hiroko, Wang Xiao-Hui, Furukawa Yusuke, Sumi Ryoichi, Kudo Takashi, Fujimura Katsuya, Iwai Toshie, Gotoh Masanori, Nakamura Mitsuru, Narimatsu Hisashi

Abstract excerpt

The human blood group i and I antigens are determined by linear and branched poly-N-acetyllactosamine structures, respectively. In erythrocytes, the fetal i antigen is converted to the adult I antigen by I-branching beta-1,6-N-acetylglucosaminyltransferase (IGnT) during development. Dysfunction of the I-branching enzyme may result in the adult i phenotype in erythrocytes. However, the I gene responsible for blood...

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Identifiers

PMID: 12468428
DOI: 10.1182/blood-2002-09-2838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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