Article
Glucocorticoid-remediable aldosteronism in a large kindred: clinical spectrum and diagnosis using a characteristic biochemical phenotype.
Annals of internal medicine - 15 May 1992
Rich G M, Ulick S, Cook S, Wang J Z, Lifton R P, Dluhy R G
Abstract excerpt
OBJECTIVE: To define the clinical spectrum of glucocorticoid-remediable aldosteronism (GRA) in a large kindred. DESIGN: Screening all at-risk relatives of a proband for GRA using a specific biochemical phenotype and collecting of medical histories of kindred members from five generations. SETTING...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- Dexamethasone
- Female
- Genes, Dominant
- Humans
- Hydrocortisone
- Hyperaldosteronism
- Hypertension
- Infant
- Male
- Middle Aged
- Pedigree
- Phenotype
- Prospective Studies
- Renin