Article
Petri net modeling of high-order genetic systems using grammatical evolution.
Bio Systems - 1 Nov 2003
Moore Jason H, Hahn Lance W
Abstract excerpt
Understanding how DNA sequence variations impact human health through a hierarchy of biochemical and physiological systems is expected to improve the diagnosis, prevention, and treatment of common, complex human diseases. We have previously developed a hierarchical dynamic systems approach based on Petri nets for generating biochemical network models that are consistent with genetic models of disease...
Topics
- Algorithms
- Artificial Intelligence
- Computer Simulation
- Gene Expression Profiling
- Genetic Predisposition to Disease
- Genetic Testing
- Humans
- Models, Genetic
- Reproducibility of Results
- Sensitivity and Specificity
- Sequence Alignment