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Article

Paired cysteine mutagenesis to establish the pattern of disulfide bonds in the functional intact secretin receptor.

The Journal of biological chemistry - 1 Apr 2005

Lisenbee Cayle S, Dong Maoqing, Miller Laurence J

Abstract excerpt

The amino-terminal domain of class B G protein-coupled receptors contains six conserved cysteine residues involved in structurally and functionally critical disulfide bonds. The mapping of these bonds has been unclear, with one pattern based on biochemical and NMR structural characterizations of refolded, nonglycosylated amino-terminal fragments, and another pattern derived from functional characterizations of...

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Identifiers

PMID: 15664984
DOI: 10.1074/jbc.M414016200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paired cysteine mutagenesis to establish the pattern of disulfide bonds in the functional intact secretin receptor.PMID 15664984Read ↗

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