Article
Bioluminescence Imaging of <i>Toxoplasma gondii</i> Infection in Living Mice Reveals Dramatic Differences between Strains
20 Jan 2005
Abstract excerpt
We examined the in vivo growth, dissemination, and reactivation of strains of the protozoan parasite Toxoplasma gondii using a bioluminescence-based imaging system. Two T. gondii strains, one with a highly virulent disease phenotype in mice (S23) and the other with a 1,000-fold-lower virulence phenotype (S22), were engineered to stably express the light-emitting protein luciferase. One clone of each wild-type...
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