Article
[Drug susceptibility of Plasmodium falciparum from polyclonal isolates].
Journal de la Societe de biologie - 1 Jan 2004
Kaddouri Halima, Jafari Sayeh, Durand Rémy, Le Bras Jacques
Abstract excerpt
Msp-1 and Msp-2 genes, each present as a unique copy in the genome of Plasmodium, contain polymorphic repeats in bloc 2. We studied allelic polymorphism of Msp-1 and Msp-2 by amplifying bloc 2 with a fluorescent primer, and analysing the fragment generated. We validated this method by mixing two...
Topics
- Africa, Western
- Alleles
- Animals
- Antigens, Protozoan
- Antimalarials
- Cells, Cultured
- Chloroquine
- DNA, Protozoan
- Drug Resistance
- Electrophoresis, Polyacrylamide Gel
- Evolution, Molecular
- France
- Gene Amplification
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Minisatellite Repeats
