Article
[Drug susceptibility of Plasmodium falciparum from polyclonal isolates].
Journal de la Societe de biologie - 1 Jan 2004
Kaddouri Halima, Jafari Sayeh, Durand Rémy, Le Bras Jacques
Abstract excerpt
Msp-1 and Msp-2 genes, each present as a unique copy in the genome of Plasmodium, contain polymorphic repeats in bloc 2. We studied allelic polymorphism of Msp-1 and Msp-2 by amplifying bloc 2 with a fluorescent primer, and analysing the fragment generated. We validated this method by mixing two cloned strains: chloroquine-susceptible HB3-Honduras and chloroquine-resistant FCM29-Cameroon. This method was then...
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