Article
Polymorphism in two merozoite surface proteins of Plasmodium falciparum isolates from Gabon.
Malaria journal - 9 May 2003
Aubouy Agnès, Migot-Nabias Florence, Deloron Philippe
Abstract excerpt
BACKGROUND: Plasmodium falciparum antigenic diversity and polymorphism confuses the issue of antimalarial vaccine development. Merozoite surface protein (MSP)-1 and -2 are two highly polymorphic vaccine candidates. Characterisation of their precise polymorphism in endemic regions may facilitate t...
Topics
- Alleles
- Animals
- Antigens, Protozoan
- Antigens, Surface
- Child
- Child, Preschool
- Gabon
- Genetic Variation
- Genotype
- Humans
- Infant
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Plasmodium falciparum
- Polymorphism, Genetic
- Protozoan Proteins