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Article

Polymorphism in two merozoite surface proteins of Plasmodium falciparum isolates from Gabon.

Malaria journal - 9 May 2003

Aubouy Agnès, Migot-Nabias Florence, Deloron Philippe

Abstract excerpt

BACKGROUND: Plasmodium falciparum antigenic diversity and polymorphism confuses the issue of antimalarial vaccine development. Merozoite surface protein (MSP)-1 and -2 are two highly polymorphic vaccine candidates. Characterisation of their precise polymorphism in endemic regions may facilitate the design of an effective vaccine. METHODS: Isolates obtained in 52 Gabonese children presenting with uncomplicated...

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Identifiers

PMID: 12773207
DOI: 10.1186/1475-2875-2-12
PMCID: PMC156643

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