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Article

Phenotypic and functional modifications of thymocytes during tumor growth.

Thymus - 1 Feb 1992

Lombardi D, Naso G, Ottavio L, Lenti L, Mardente S, Pontieri G M

Abstract excerpt

Thymocytes (T) from mice bearing the syngeneic tumor 3LL inhibit the immune response to SRBC by syngeneic splenocytes derived from control mice and cultured in Mishell and Dutton's antibody forming systems. T from control mice are devoid of this capacity but acquire it after in vitro incubation with tumor cells. It has been shown that metabolites of arachidonic acid (PGE-2, LTB-4 and LTC-4) synthesized in excess...

Topics

Animals
Blood Physiological Phenomena
Dinoprostone
Immune Tolerance
Leukotrienes
Lung Neoplasms
Male
Mice
Mice, Inbred C57BL
Neoplasms, Experimental
Phenotype
T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1566282

Genes

LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1566282-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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