Article
Phenotypic and functional modifications of thymocytes during tumor growth.
Thymus - 1 Feb 1992
Lombardi D, Naso G, Ottavio L, Lenti L, Mardente S, Pontieri G M
Abstract excerpt
Thymocytes (T) from mice bearing the syngeneic tumor 3LL inhibit the immune response to SRBC by syngeneic splenocytes derived from control mice and cultured in Mishell and Dutton's antibody forming systems. T from control mice are devoid of this capacity but acquire it after in vitro incubation with tumor cells. It has been shown that metabolites of arachidonic acid (PGE-2, LTB-4 and LTC-4) synthesized in excess...
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