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Article

Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.

Immunological reviews - 1 Feb 2005

Pesu Marko, Candotti Fabio, Husa Matthew, Hofmann Sigrun R, Notarangelo Luigi D, O'Shea John J

Abstract excerpt

The recent elucidation of the multiple molecular mechanisms underlying severe combined immunodeficiency (SCID) is an impressive example of the power of molecular medicine. Analysis of patients and the concomitant generation of animal models mimicking these disorders have quickly provided great insights into the pathophysiology of these potentially devastating illnesses. In this review, we summarize the...

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Source

Identifiers

PMID: 15661026
DOI: 10.1111/j.0105-2896.2005.00220.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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