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Coccidioides posadasii contains a single 1,3-beta-glucan synthase gene that appears to be essential for growth.

Eukaryotic cell - 1 Jan 2005

Kellner Ellen M, Orsborn Kris I, Siegel Erin M, Mandel M Alejandra, Orbach Marc J, Galgiani John N

Abstract excerpt

1,3-beta-Glucan synthase is responsible for the synthesis of beta-glucan, an essential cell wall structural component in most fungi. We sought to determine whether Coccidioides posadasii possesses genes homologous to known fungal FKS genes that encode the catalytic subunit of 1,3-beta-glucan synthase. A single gene, designated FKS1, was identified, and examination of its predicted protein product showed a high...

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Identifiers

PMID: 15643067
DOI: 10.1128/EC.4.1.111-120.2005
PMCID: PMC544152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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