Article
[A novel gene in APOA1/C3/A4/A5 cluster: apolipoprotein A5].
Yi chuan = Hereditas - 1 Nov 2004
Liu He-Kun, Zhang Si-Zhong, Su Zhi-Guang, Ma Yong-Xin, Wang Chun-Ting
Abstract excerpt
Using methods of comparative and functional genomics, a new gene coding for apolipoprotein A5 was identified in the vicinity of APOA1/C3/A4 cluster on human chromosome 11q23 by Pennaccio team and Vliet team. The open reading frame of human APOA5 encoded a 366-amino acid protein with high sequence homology to mouse Apoa5 and human APOA4. Mice expressing a human APOA5 transgene showed a decrease in plasma...
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