Article
A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Stephens Jeffrey W, Dhamrait Sukhbir S, Acharya Jayshree, Humphries Steve E, Hurel Steven J
Abstract excerpt
AIMS: The D allele of the ACE I/D gene variant is associated with higher tissue and serum ACE activity. Previously, studies have suggested an association between the D allele with the microvascular complications of diabetes. The aim of this study was to explore the impact of this genotype in relation to clinically manifest peripheral neuropathy (PN) in a cohort of subjects with type 2 diabetes mellitus (type 2...
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