Article
Plasmodium falciparum resistant to chloroquine and to pyrimethamine in Comoros.
Parasite (Paris, France) - 1 Dec 2004
Randrianarivelojosia M, Raherinjafy R H, Migliani R, Mercereau-Puijalon O, Ariey F, Bedja S A
Abstract excerpt
We report the outcome of chloroquine treatment and the prevalence of mutations at codon 86 of the pfmdr1 gene, at codon 76 of the pfcrt gene, and at codon 108 of the pfdhfr gene in clinical isolates of Plasmodium falciparum collected from 30 children under 10 years of age living in the Comoros Union. This in vivo study was carried out in February and March 2001 in Moroni. Chloroquine treatment failed in 23...
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