Article
A comprehensive study on the immunological reactivity of the Hsp90 molecular chaperone.
Journal of biochemistry - 1 Nov 2004
Kawano Toshihiro, Kobayakawa Takeshi, Fukuma Yutaka, Yukitake Hideharu, Kikuchi Yuichiro, Shoji Mikio, Nakayama Koji, Mizuno Akio, Takagi Takashi, Nemoto Takayuki K
Abstract excerpt
Periodontitis is a chronic infectious disease, Porphyromonas gingivalis being the most implicated pathogen. In the present study, we investigated the role of P. gingivalis HtpG (PgHtpG), a bacterial ortholog of mammalian Hsp90, in the growth of P. gingivalis and also assessed the immunological cross-reactivity of the members of the Hsp90 family. Antiserum against rat liver Hsp90 potently reacted with yeast Hsp90,...
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