Article
The R protein of SARS-CoV: analyses of structure and function based on four complete genome sequences of isolates BJ01-BJ04.
Genomics, proteomics & bioinformatics - 1 May 2003
Xu Zuyuan, Zhang Haiqing, Tian Xiangjun, Ji Jia, Li Wei, Li Yan, Tian Wei, Han Yujun, Wang Lili, Zhang Zizhang, Xu Jing, Wei Wei, Zhu Jingui, Sun Haiyan, Zhang Xiaowei, Zhou Jun, Li Songgang, Wang Jun, Wang Jian, Bi Shengli, Yang Huanming
Abstract excerpt
The R (replicase) protein is the uniquely defined non-structural protein (NSP) responsible for RNA replication, mutation rate or fidelity, regulation of transcription in coronaviruses and many other ssRNA viruses. Based on our complete genome sequences of four isolates (BJ01-BJ04) of SARS-CoV from Beijing, China, we analyzed the structure and predicted functions of the R protein in comparison with 13 other...
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