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Article

Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jan 2005

Powell C Bethan, Kenley Eric, Chen Lee-May, Crawford Beth, McLennan Jane, Zaloudek Charles, Komaromy Miriam, Beattie Mary, Ziegler John

Abstract excerpt

PURPOSE: Women who carry deleterious mutations of BRCA1 or BRCA2 genes have up to a 54% lifetime risk of developing ovarian cancer. After childbearing, women at high risk increasingly choose bilateral risk-reducing salpingo-oophorectomy (RRSO). Two recent studies of BRCA mutation carriers reporte...

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Source

Identifiers

PMID: 15625367
DOI: 10.1200/JCO.2005.04.109

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15625367-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancy.PMID 15625367Read ↗

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