Article
Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation.
Brain : a journal of neurology - 1 Apr 2005
Boeve Bradley F, Tremont-Lukats Ivo W, Waclawik Andrew J, Murrell Jill R, Hermann Bruce, Jack Clifford R, Shiung Maria M, Smith Glenn E, Nair Anil R, Lindor Noralane, Koppikar Vinaya, Ghetti Bernardino
Abstract excerpt
The background to this study began with the reporting of two Japanese kindreds with the S305N tau mutation. Although the pathological findings in the autopsied cases were well characterized, only limited ante-mortem data were presented. In this study, longitudinal characterization was carried out in two siblings of European ancestry found to have frontotemporal dementia and parkinsonism linked to chromosome 17...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.