Article
Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster.
The Journal of biological chemistry - 4 Mar 2005
Jakimowicz Piotr, Cheesman Myles R, Bishai William R, Chater Keith F, Thomson Andrew J, Buttner Mark J
Abstract excerpt
WhiD is required for the late stages of sporulation in the Gram-positive bacterium Streptomyces coelicolor. WhiD is a member of the WhiB-like family of putative transcription factors that are present throughout the actinomycetes but absent from other organisms. This family of proteins has four near-invariant cysteines, suggesting that these residues might act as ligands for a metal cofactor. Overexpressed WhiD,...
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