Article
[ACE and AGTR1 genes polymorphisms in left ventricular hypertrophy pathogenesis in humans].
Molekuliarnaia biologiia - 1 Jan 2000
Makeeva O A, Puzyrev K V, Pavliukova E N, Koshel'skaia O A, Golubenko M V, Efimova E V, Kucher A N, Tsimbaliuk I V, Karpov R S, Puzyrev V P
Abstract excerpt
The role of A2350G polymorphism in exon 17 of the ACE gene and A1166C - in 3'-UTR of the AGTR1 in the pathogenesis of left ventricular hypertrophy was studied in patients with essential hypertension (EH) and arterial hypertension combined with diabetes mellitus type 2 (AH + DM2). Patients with EH and AH + DM2 did not differ from the control sample of healthy individuals by allele or genotype frequencies. However,...
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