Article
[Polymorphic markers of GNB3 (C825T), AGTR1 (A1166C) and ACE (A2350G and I/D) genes in patients with arterial hypertension combined with diabetes mellitus type 2].
Terapevticheskii arkhiv - 1 Jan 2004
Karpov R S, Puzyrev K V, Koshel'skaia O A, Makeeva O A, Suslova T E, Efimova E V, Fal'kovskaia A Iu, Atroshenkov A V
Abstract excerpt
AIM: To elicit correlations of polymorphic markers of GNB3 (C825T), AGTR1 (A1166C), ACE (A2350G and I/D) genes with arterial pressure, left ventricular hypertrophy (LVH) and blood concentrations of proinflammatory cytokines in hypertensive patients with diabetes mellitus type 2 (DM2). MATERIAL AND METHODS: Clinical parameters (24-h arterial pressure profile, echocardiographic findings, immunoenzymes level) were...
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