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Article

Hyperthermia enhances CD95-ligand gene expression in T lymphocytes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2005

Cippitelli Marco, Fionda Cinzia, Di Bona Danilo, Piccoli Mario, Frati Luigi, Santoni Angela

Abstract excerpt

Hyperthermia represents an interesting therapeutic strategy for the treatment of tumors. Moreover, it is able to regulate several aspects of the immune response. Fas (APO-1/CD95) and its ligand (FasL) are cell surface proteins whose interaction activates apoptosis of Fas-expressing targets. In T cells, the Fas-Fas-L system regulates activation-induced cell death, is implicated in diseases in which lymphocyte...

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Source

Identifiers

PMID: 15611244
DOI: 10.4049/jimmunol.174.1.223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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