Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced DNA repair capacity in laryngeal cancer subjects. A comparison of phenotypic and genotypic results.

Advances in oto-rhino-laryngology - 1 Jan 2005

Gajecka Marzena, Rydzanicz Malgorzata, Jaskula-Sztul Renata, Wierzbicka Martgorzata, Szyfter Witold, Szyfter Krzysztof

Abstract excerpt

The impact of genetic factors on laryngeal cancer risk was studied in relation to DNA repair capacity on the phenotypic and genotypic level. DNA lesions induced by bleomycin or S9-activated benzo[a]pyrene were determined in blood lymphocytes using the alkaline comet assay. Laryngeal cancer subjects (n = 52) were shown to have higher levels of spontaneous and mutagen-induced DNA damage as compared to healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Comet Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Laryngeal Neoplasms

Share to Poland

Share to Probability

Share to Reference Values

Share to Survival Analysis

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 15608415
DOI: 10.1159/000082460

Genes

XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced DNA repair capacity in laryngeal cancer subjects. A comparison of phenotypic and genotypic results.PMID 15608415Read ↗

Do we know enough about the genetic involvement in laryngeal cancer susceptibility and prognostic outcome?Semantic proximity Read ↗

Polymorphisms of DNA repair genes and risk of squamous cell carcinoma of the head and neck in young adults.Semantic proximity Read ↗

Behind XRCC1 Arg399Gln polymorphism: protection factor of laryngeal cancerSemantic proximity Read ↗

The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults.Semantic proximity Read ↗

DNA damage and nucleotide excision repair capacity in healthy individuals.Semantic proximity Read ↗

Micronucleus frequencies in lymphocytes and buccal epithelial cells from patients having head and neck cancer and their first-degree relativesSemantic proximity Read ↗

In vitro benzo[a]pyrene diol epoxide-induced DNA damage and chromosomal aberrations in primary lymphocytes, smoking, and risk of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Possible involvement of XPA in repair of oxidative DNA damage deduced from analysis of damage, repair and genotype in a human population study.Semantic proximity Read ↗

Influence of genetic polymorphisms on frequency of micronucleated buccal epithelial cells in leukoplakia patients.Semantic proximity Read ↗

Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk.Semantic proximity Read ↗

CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell carcinoma.Semantic proximity Read ↗

Development and validation of a modified comet assay to phenotypically assess nucleotide excision repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.