Article
Laboratory animal welfare: cage enrichment and mouse behaviour.
Nature - 16 Dec 2004
Wolfer David P, Litvin Oxana, Morf Samuel, Nitsch Roger M, Lipp Hans-Peter, Würbel Hanno
Abstract excerpt
Mice housed in standard cages show impaired brain development, abnormal repetitive behaviours (stereotypies) and an anxious behavioural profile, all of which can be lessened by making the cage environment more stimulating. But concerns have been raised that enriched housing might disrupt standardization and so affect the precision and reproducibility of behavioural-test results (for example, see ref. 4). Here we...
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