Article
Clinical, cellular, and molecular characterisation of cardiac rhabdomyoma in tuberous sclerosis.
Cardiology in the young - 1 Aug 2021
Al Kindi Hamood N, Ibrahim Ayman M, Roshdy Mohamed, Abdelghany Besra S, Yehia Dina, Masoud Ahmed Nageeb, Simry Walid, Aguib Yasmine, Yacoub Magdi H
Abstract excerpt
BACKGROUND: Rhabdomyoma is the most common cardiac tumour in children. It is usually associated with tuberous sclerosis complex caused by mutations in TSC-1 or TSC-2 genes. This tumour typically regresses by unknown mechanisms; however, it may cause inflow or outflow obstruction that necessitates urgent surgery. Here we investigate the clinical features and the genetic analysis of patients with tuberous sclerosis...
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