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Article

Relative concentrations of hK2/PSA mRNA in benign and malignant prostatic tissue

14 Dec 2004

Abstract excerpt

BACKGROUND: Prostate-specific antigen (PSA/KLK3) and human kallikrein 2 (hK2/KLK2) belong to the human kallikrein gene family. These two highly homologous genes are specifically expressed in the prostate under androgen control. Expression of these is regulated by similar mechanisms but changes in their relative expression have been observed in prostate cancer. METHODS: We determined the relative levels of PSA and...

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PMID: 15599939
DOI: 10.1002/pros.20194

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