Article
Soluble CD14 receptor expression and monocyte heterogeneity but not the C-260T CD14 genotype are associated with severe acute pancreatitis.
Critical care medicine - 1 Dec 2004
Rahman Sakhawat H, Salter Gwyneth, Holmfield John H M, Larvin Michael, McMahon Michael J
Abstract excerpt
OBJECTIVE: Soluble CD14 is derived from a membrane glycoprotein, and it enhances endothelial cytokine responses to lipopolysaccharide. We studied the role of soluble CD14 in the pathogenesis of the systemic inflammatory response associated with acute pancreatitis, to determine whether altered exp...
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