Article
Cytochrome c maturation proteins are critical for in vivo growth of Legionella pneumophila.
FEMS microbiology letters - 15 Dec 2004
Naylor Jennifer, Cianciotto Nicholas P
Abstract excerpt
Legionella pneumophila, an intracellular parasite of macrophages and protozoa, requires iron for extra- and intracellular growth. In a new screen of a mutant library of L. pneumophila for strains defective for growth on agar media lacking supplemental iron, seven mutants were obtained. All of the mutants had a disruption in the cytochrome c maturation (ccm) locus; two had insertions in ccmB, two in ccmC, and...
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